National Health Research Institutes (NHRI)

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The NHRI consists of 10 research divisions and 4 departments. These divisions range from the common problems such as aging, cancer, infectious diseases, mental disorders, occupational diseases, to health policy.

National Health Research Institutes (NHRI)'s Articles

National Health Research Institutes (NHRI)'s articles RSS

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Correction: Periostin promotes ovarian cancer metastasis by enhancing M2 macrophages and cancer-associated fibroblasts via integrin-mediated NF-κB and TGF-β2 signaling

Authors: Sheng-Chieh Lin, Yi-Chu Liao, Po-Ming Chen, Ya-Yu Yang, Yi-Hsiang Wang, Shiao-Lin Tung, Chi-Mu Chuang, Yu-Wen Sung, Te-Hsuan Jang, Shuang-En Chuang and Lu-Hai Wang

Citation: Journal of Biomedical Science 2023 30:54

Content type: Correction Published on: 12 July 2023

The original article was published in Journal of Biomedical Science 2022 29:109
Krüppel-like factor 10 modulates stem cell phenotypes of pancreatic adenocarcinoma by transcriptionally regulating notch receptors

Authors: Yi-Chih Tsai, Kung Hung Cheng, Shih Sheng Jiang, John R. Hawse, Shun En Chuang, Su Liang Chen, Tze-Sing Huang and Hui-Ju Ch’ang

Citation: Journal of Biomedical Science 2023 30:39

Content type: Research Published on: 12 June 2023
Trends in energy and macronutrient intake among Taiwanese older adults in 1999–2000, 2005–2008 and 2013–2016 periods

Authors: Chih-Hsueh Lin, Hsing-Yi Chang, Tsai-Chung Li, Chiu-Shong Liu, Wen-Yuan Lin, Meng-Chih Lee, Li-Na Liao, Chia-Ing Li, Chih-Yi Hsiao, Hsin-Ling Fang, Wen-Tzu Wu and Cheng-Chieh Lin

Citation: BMC Public Health 2023 23:871

Content type: Research Published on: 12 May 2023
Periostin promotes ovarian cancer metastasis by enhancing M2 macrophages and cancer-associated fibroblasts via integrin-mediated NF-κB and TGF-β2 signaling

Authors: Sheng-Chieh Lin, Yi-Chu Liao, Po-Ming Chen, Ya-Yu Yang, Yi-Hsiang Wang, Shiao-Lin Tung, Chi-Mu Chuang, Yu-Wen Sung, Te-Hsuan Jang, Shuang-En Chuang and Lu-Hai Wang

Citation: Journal of Biomedical Science 2022 29:109

Content type: Research Published on: 22 December 2022

The Correction to this article has been published in Journal of Biomedical Science 2023 30:54
Cancer-derived extracellular succinate: a driver of cancer metastasis

Authors: Cheng-Chin Kuo, Jing-Yiing Wu and Kenneth K. Wu

Citation: Journal of Biomedical Science 2022 29:93

Content type: Review Published on: 7 November 2022
PTEN regulates invasiveness in pancreatic neuroendocrine tumors through DUSP19-mediated VEGFR3 dephosphorylation

Authors: Tsung-Ming Chang, Pei-Yi Chu, Hui-You Lin, Kuo-Wei Huang, Wen-Chun Hung, Yan-Shen Shan, Li-Tzong Chen and Hui-Jen Tsai

Citation: Journal of Biomedical Science 2022 29:92

Content type: Research Published on: 6 November 2022
Association of advanced paternal age with lung function at school age

Authors: Chun-Chun Gau, Hsin-Ju Lee, Hung-Yi Lu, Chao-Yi Wu, Hsin-Yi Huang, Hui-Ju Tsai and Tsung-Chieh Yao

Citation: Respiratory Research 2022 23:259

Content type: Research Published on: 20 September 2022
AKT phosphorylation as a predictive biomarker for PI3K/mTOR dual inhibition-induced proteolytic cleavage of mTOR companion proteins in small cell lung cancer

Authors: Ming-Chun Hung, Wan-Ping Wang and Ya-Hui Chi

Citation: Cell & Bioscience 2022 12:122

Content type: Research Published on: 2 August 2022
Aryl hydrocarbon receptor activation-mediated vascular toxicity of ambient fine particulate matter: contribution of polycyclic aromatic hydrocarbons and osteopontin as a biomarker

Authors: Chia-Chi Ho, Wei-Te Wu, Yi-Jun Lin, Chen-Yi Weng, Ming-Hsien Tsai, Hui-Ti Tsai, Yu-Cheng Chen, Shaw-Fang Yet and Pinpin Lin

Citation: Particle and Fibre Toxicology 2022 19:43

Content type: Research Published on: 23 June 2022
MicroRNA-485-5p targets keratin 17 to regulate oral cancer stemness and chemoresistance via the integrin/FAK/Src/ERK/β-catenin pathway

Authors: Te-Hsuan Jang, Wei-Chieh Huang, Shiao-Lin Tung, Sheng-Chieh Lin, Po-Ming Chen, Chun-Yu Cho, Ya-Yu Yang, Tzu-Chen Yen, Guo-Hsuen Lo, Shuang-En Chuang and Lu-Hai Wang

Citation: Journal of Biomedical Science 2022 29:42

Content type: Research Published on: 15 June 2022
Induction of high affinity monoclonal antibodies against SARS-CoV-2 variant infection using a DNA prime-protein boost strategy

Authors: Chen-Yi Chiang, Mei-Yu Chen, Chia-Wei Hsu, Chia-Yeh Liu, Yu-Wen Tsai, Hung-Chun Liao, Jia-Ying Yan, Zih-Shiuan Chuang, Hsin-I. Wang, Chien-Hsiung Pan, Chia-Yi Yu, Guann-Yi Yu, Ching-Len Liao, Shih-Jen Liu and Hsin-Wei Chen

Citation: Journal of Biomedical Science 2022 29:37

Content type: Research Published on: 9 June 2022
A new scoring system facilitating diagnosis of oral squamous malignancy on biopsy specimens

Authors: Cheng-Lin Wu, Cheng-Chih Huang, Shang-Yin Wu, Shih-Sheng Jiang, Fang-Yu Tsai and Jenn-Ren Hsiao

Citation: BMC Oral Health 2022 22:165

Content type: Research article Published on: 6 May 2022
Cysteine-rich protein 2 deficiency attenuates angiotensin II-induced abdominal aortic aneurysm formation in mice

Authors: Chung-Huang Chen, Hua-Hui Ho, Wei-Cheng Jiang, Wai-Sam Ao-Ieong, Jane Wang, Alexander N. Orekhov, Igor A. Sobenin, Matthew D. Layne and Shaw-Fang Yet

Citation: Journal of Biomedical Science 2022 29:25

Content type: Research Published on: 12 April 2022
Measuring distance from the incisors to the esophageal cancer by FDG PET/CT: endoscopy as the reference

Authors: Szu-Wei Hsu, Jeffrey S. Chang, Wei-Lun Chang, Forn-Chia Lin and Nan-Tsing Chiu

Citation: BMC Gastroenterology 2022 22:126

Content type: Research Published on: 17 March 2022
Combination treatment of docetaxel with caffeic acid phenethyl ester suppresses the survival and the proliferation of docetaxel-resistant prostate cancer cells via induction of apoptosis and metabolism interference

Authors: Yu-Ke Fu, Bi-Juan Wang, Jen-Chih Tseng, Shih-Han Huang, Ching-Yu Lin, Ying-Yu Kuo, Tzyh-Chyuan Hour and Chih-Pin Chuu

Citation: Journal of Biomedical Science 2022 29:16

Content type: Research Published on: 23 February 2022
Restoration of 5-methoxytryptophan protects against atherosclerotic chondrogenesis and calcification in ApoE^−/− mice fed high fat diet

Authors: Guan-Lin Lee, Tsai-Lien Liao, Jing-Yiing Wu, Kenneth K. Wu and Cheng-Chin Kuo

Citation: Journal of Biomedical Science 2021 28:74

Content type: Research Published on: 8 November 2021
AUY922 induces retinal toxicity through attenuating TRPM1

Authors: Che-Hung Shen, Chi-Che Hsieh, Kuan-Ying Jiang, Chih-Yu Lin, Nai-Jung Chiang, Ting-Wei Li, Chun-Ting Yen, Wan-Ju Chen, Daw-Yang Hwang and Li-Tzong Chen

Citation: Journal of Biomedical Science 2021 28:55

Content type: Research Published on: 23 July 2021
Mitochondrial protein CMPK2 regulates IFN alpha-enhanced foam cell formation, potentially contributing to premature atherosclerosis in SLE

Authors: Jenn-Haung Lai, Li-Feng Hung, Chuan-Yueh Huang, De-Wei Wu, Chien-Hsiang Wu and Ling-Jun Ho

Citation: Arthritis Research & Therapy 2021 23:120

Content type: Research article Published on: 19 April 2021
Insulin-like growth factor binding protein 3 promotes radiosensitivity of oral squamous cell carcinoma cells via positive feedback on NF-κB/IL-6/ROS signaling

Authors: Ssu-Han Wang, Yu-Lin Chen, Jenn-Ren Hsiao, Fang-Yu Tsai, Shih Sheng Jiang, Alan Yueh-Luen Lee, Hui-Jen Tsai and Ya-Wen Chen

Citation: Journal of Experimental & Clinical Cancer Research 2021 40:95

Content type: Research Published on: 13 March 2021
Sex differences in the trajectories of and factors related to extracurricular sport participation and exercise: a cohort study spanning 13 years

Authors: Wen-Chi Wu, Ling-Yin Chang, Dih-Ling Luh, Chi-Chen Wu, Fiona Stanaway, Lee-Lan Yen and Hsing-Yi Chang

Citation: BMC Public Health 2020 20:1639

Content type: Research article Published on: 2 November 2020